The anterior Hox gene ceh-13 and elt-1/GATA activate the posterior Hox genes nob-1 and php-3 to specify posterior lineages in the C. elegans embryo
John I. Murray, Elicia A. Preston, Jeremy P. Crawford, Jonathan D. Rumley, Prativa Amom, Breana D. Anderson, Priya Sivaramakrishnan, Shaili D. Patel, Barrington Alexander Bennett, Teddy D. Lavon, Erin Hsiao, Felicia Peng, Amanda L. Zacharias
The paper identifies regulatory mechanisms for posterior Hox genes nob-1 and php-3 in C. elegans, showing that anterior Hox gene ceh-13 and other factors activate these genes, influencing cell lineage and position.
PLoS Genetics · May 2, 2022Peer-reviewedGenetics