Amanda L. Zacharias

This study models early IAV infection in alveolar organoids, revealing conserved AT2 cell responses and uninfected cell state transitions driven by inflammation.

The paper shows that alveolar-basal intermediates (ABI) drive pulmonary fibrosis by coordinating a pro-fibrotic signaling niche in silicosis.

The paper shows that the ARID1A-containing BAF complex is essential for lung development, proximal-distal axis specification, and cell fate acquisition during respiratory development.

This paper introduces an optogenetic system to modulate mitochondrial membrane potential by forming inter-mitochondrial contacts, showing it mitigates blue light damage in retinal cells and C. elegans.

The paper identifies transcription factors that regulate anterior gene expression in C. elegans embryos through cis-regulatory elements and enhancer analysis.

The paper identifies regulatory mechanisms for posterior Hox genes nob-1 and php-3 in C. elegans, showing that anterior Hox gene ceh-13 and other factors activate these genes, influencing cell lineage and position.