CCR4+low-density neutrophils define a novel immunosuppressive subset associated with breast cancer progression and early mortality
Bruna Filipa Correia, D.S.C.P. Grosa, Rute Salvador, Telma Martins, Marina Miguel Vitorino, Jorge M. Mendes, Andreia Lopes, Marta Parreira, Beatriz Martins, Guilherme Vilhais, Mariana Marques, Maria Gabriela Gasparinho, Sofia Cristóvão‐Ferreira, Diana P. Saraiva, Nídea de Sousa, , Maria Guadalupe Cabral
The paper identifies a novel immunosuppressive neutrophil subset, CCR4+LDN, associated with breast cancer progression and mortality, and shows its potential as a biomarker and therapeutic target.
bioRxiv · Sep 24, 2026 · PreprintImmunology