Mariana Marques

The paper identifies a novel immunosuppressive neutrophil subset, CCR4+LDN, associated with breast cancer progression and mortality, and shows its potential as a biomarker and therapeutic target.

This study uses CRISPRi to silence Mtb genes involved in peptidoglycan modifications, showing their role in β-lactam resistance and host immune responses.

The paper introduces a capillary-based subcellular sampling method combined with LC-MS to analyze stress granule proteomes in single cells, identifying 405 high-confidence proteins with minimal cytosolic contamination.

This study shows that stress granule formation during FMDV infection is independent of innate immune activation, and that preventing their disassembly reduces viral replication.