HIV integrase compacts viral DNA into biphasic condensates
Pauline J. Kolbeck, Marjolein de Jager, Margherita Gallano, Tine Brouns, Ben Bekaert, Wout Frederickx, Sebastian F. Konrad, Siska Van Belle, Frauke Christ, Steven De Feyter, Zeger Debyser, Laura Filion, Jan Lipfert, Willem Vanderlinden
This study shows HIV integrase compacts viral DNA into biphasic condensates, with the core susceptible to inhibitors and the outer layer resistant.
bioRxiv · Mar 15, 2024 · PreprintBiophysics