Author

Ben Jenkins

University of Cambridge

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Genetics· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Albert KoulmaniD· 1 shared Alessandra FerrariiD· 1 shared Alexander MörseburgiD· 1 shared Beatriz Romartínez-AlonsoiD· 1 shared Brian LamiD· 1 shared Claudia LangenbergiD· 1 shared Debra RimmingtoniD· 1 shared Derek A. ManniD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperGenetics

Albert KoulmanORCID

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1 paper

Recent·Most cited

Damaging mutations in LXRα uncouple lipogenesis from hepatotoxicity and implicate hepatic cholesterol sensing in human liver health

Sam M. Lockhart, Milan Mušo, Ilona Zvetkova, Brian Lam, Alessandra Ferrari, Erik Schoenmakers, Katie Duckett, Jack Leslie, Beatriz Romartínez-Alonso, John A. Tadross, Raina Jia, Eugene J. Gardner, Katherine A. Kentistou, Yajie Zhao, Felix R. Day, , Stephen O’Rahilly

This study identifies damaging LXRα mutations linked to reduced triglycerides but increased liver enzyme levels and hepatotoxicity, suggesting LXR's role in liver health and cautioning against its inhibition for MASLD treatment.

bioRxiv · Apr 28, 2024 · PreprintGenetics