Ilona Zvetkova

This study identifies damaging LXRα mutations linked to reduced triglycerides but increased liver enzyme levels and hepatotoxicity, suggesting LXR's role in liver health and cautioning against its inhibition for MASLD treatment.

This study identifies Mir483 as a growth suppressor and metabolic regulator that antagonizes its host gene Igf2 through IGF1 signaling, revealing a novel mechanism of growth control.

This study identifies mesenchymal Igf2 as a critical paracrine regulator of pancreatic growth and function through in vivo and ex vivo experiments.

This study creates a mouse model of SHORT syndrome by introducing a Pik3r1 mutation, revealing lipodystrophic insulin resistance without dyslipidemia.