Author

Benoit Lechat

VIB-KU Leuven Center for Cancer Biology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Anna A. SablinaiD· 1 shared Edward C. StitesiD· 1 shared Emiel Van BoxeliD· 1 shared Greetje Vande VeldeiD· 1 shared Peihua ZhaoiD· 1 shared Raj Nayan SewduthiD· 1 shared Tonči IvaniševićiD· 1 shared Wout MagitsiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperCancer Biology

Anna A. SablinaORCID

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1 paper

Recent·Most cited

Increased dosage of wild-type KRAS protein drives KRAS-mutant lung tumorigenesis and drug resistance

Tonči Ivanišević, Wout Magits, Yan Ma, Peihua Zhao, Emiel Van Boxel, Benoit Lechat, Edward C. Stites, Greetje Vande Velde, Raj Nayan Sewduth, Anna A. Sablina

This study shows that increased wild-type KRAS protein dosage in KRAS-mutant lung cancer drives tumor growth and drug resistance, with vascular changes mediated by mTOR pathway activation.

bioRxiv · Feb 27, 2024 · PreprintCancer Biology