Greetje Vande Velde

The paper establishes a clinically relevant M. avium model using clinical isolates and longitudinal imaging to evaluate anti-mycobacterial drugs in vivo.

This study shows that increased wild-type KRAS protein dosage in KRAS-mutant lung cancer drives tumor growth and drug resistance, with vascular changes mediated by mTOR pathway activation.

This study evaluates the effects of trisomy and GTE-EGCG treatment on multiple systems in a Down syndrome mouse model, finding that treatment exacerbates trisomic phenotypes rather than rescuing them.

This study examines cardiopulmonary and immunological changes in Ts65Dn mice and evaluates the effects of prenatal GTE-EGCG treatment on these traits.

This paper introduces a bioluminescence-based ex vivo burn wound model to assess antibacterial compounds in real-time, validated with an engineered lysin.

The paper describes the development of a broadly neutralizing antibody, XVR011, effective against SARS-CoV-2 and its variants in animal models.

This study shows EGCG treatment improves facial dysmorphology in DS mouse models and humans but warns against non-prescribed use due to variable outcomes.