Biophysical basis for the induction of glioblastoma-like phenotype in astrocytes
Laurent Starck, Melika Sarem, Bernd Heimrich, Ritwick Sawarkar, Marie‐Françoise Ritz, Gregor Hütter, Venkatram Prasad Shastri
The paper shows that nanoroughness induces a glioblastoma-like phenotype in astrocytes through spheroid formation, MMP2 activation, and gene expression changes.
bioRxiv · Jul 31, 2023 · PreprintNeuroscience