The role of the roof plate for mesencephalic trigeminal neuron
Clemens Lumper, Artemis Koumoundourou, Max Peter Neukum, Steffen Rauchfuss, Ulrike Kohler, Bernhard Hirt, Anthony Graham, Andrea Wizenmann
This study investigates how MTN axons avoid crossing the roof plate, finding that SLIT2-ROBO2 signaling prevents this and maintains cell bodies near the roof plate.
bioRxiv · May 7, 2026 · PreprintDevelopmental Biology