Sub-nucleosomal organization in urine cell-free DNA
Havell Markus, Jun Zhao, Tania Contente‐Cuomo, Michelle D. Stephens, Elizabeth A. Raupach, Ahuva Odenheimer-Bergman, Sydney C Connor, Bradon R. McDonald, Bethine Moore, Elizabeth D. Hutchins, Marissa I. McGilvrey, Michelina C. de la Maza, Kendall R. Van Keuren‐Jensen, Patrick Pirrotte, Ajay Goel, , Muhammed Murtaza
This study characterizes urine cfDNA fragmentation patterns and shows they reflect sub-nucleosomal organization, with potential for cancer diagnostics.
Science Translational Medicine · Feb 17, 2021Peer-reviewedGenomics