Elizabeth A. Raupach

Pancreatic tumor microenvironment reprogramming via alloantigen-expressing virotherapy elicits tumor rejection and improves immunotherapy response

Oncolytic virus-based delivery of an alloantigen improves antitumor immunity and synergizes with immune checkpoint inhibitors in pancreatic cancer.

Repeat Systemic Delivery of Cross-Neutralization Resistant Synthetic Vesiculoviruses Immunomodulates the Tumor Microenvironment

A glycoprotein-engineered vesiculovirus platform circumvents neutralizing antibodies, enabling repeat intravenous dosing and sustained anti-tumor immunity in preclinical models.

Sub-nucleosomal organization in urine cell-free DNA

This study characterizes urine cfDNA fragmentation patterns and shows they reflect sub-nucleosomal organization, with potential for cancer diagnostics.

Bisbee: A proteomics validated analysis package for detecting differential splicing, identifying splice outliers, and predicting splice event protein effects

Bisbee detects differential splicing and identifies splice outliers with improved sensitivity and specificity using proteomics validated methods.

The Paf1 complex broadly impacts the transcriptome of Saccharomyces cerevisiae

This study investigates the role of the Paf1 complex in regulating the transcriptome of Saccharomyces cerevisiae, revealing its impact on both coding and noncoding transcripts through transcriptional and post-transcriptional mechanisms.