Efficient Derivation of Immortalized, Isogenic Cell Lines from Genetically Defined Murine Hepatoblastomas
Huabo Wang, Jie Li Lu, Keyao Chen, Bingwei Ma, Colin Henchy, Jessica Knapp, Sarangarajan Ranganathan, Edward V. Prochownik
This paper describes the generation of isogenic murine hepatoblastoma cell lines with defined oncogenic drivers, which retain tumorigenicity and express endothelial markers under hypoxic conditions.
Biochemical and Biophysical Research Communications · Aug 13, 2025Peer-reviewedCancer Biology