Author
Children's Hospital of Pittsburgh
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
4 papers
Recent·Most cited
Keyao Chen, Ahmet Toksoz, Colin Henchy, Jessica Knapp, Jie Li Lu, Sarangarajan Ranganathan, Huabo Wang, Edward V. Prochownik
This paper describes the generation of genetically-defined murine hepatoblastoma cell lines with angiogenic potential and reports their tumorigenic properties and drug sensitivities.
Cancers · Sep 14, 2025Peer-reviewedCancer Biology
Huabo Wang, Jie Li Lu, Keyao Chen, Bingwei Ma, Colin Henchy, Jessica Knapp, Sarangarajan Ranganathan, Edward V. Prochownik
This paper describes the generation of isogenic murine hepatoblastoma cell lines with defined oncogenic drivers, which retain tumorigenicity and express endothelial markers under hypoxic conditions.
Biochemical and Biophysical Research Communications · Aug 13, 2025Peer-reviewedCancer Biology
Huabo Wang, Bingwei Ma, Taylor Stevens, Jessica Knapp, Jie Li Lu, Edward V. Prochownik
This study identifies MYC and MAX binding near transcriptional end sites (TESs) and shows their role in regulating gene expression, read-through transcription, and intragenic contacts.
Advanced Science · May 30, 2025Peer-reviewedMolecular Biology
Keyao Chen, Huabo Wang, Bingwei Ma, Jessica Knapp, Colin Henchy, Jie Li Lu, Taylor Stevens, Sarangarajan Ranganathan, Edward V. Prochownik
The paper identifies Gas1 as a suppressor of hepatoblastoma tumorigenesis by showing its restoration inhibits tumor growth in mice and cell lines, and identifies a common set of B-Y-N regulated genes.
American Journal Of Pathology · Jan 29, 2025Peer-reviewedCancer Biology