Author

Boris N Reznik

Moderna Therapeutics (United States)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Andrea FrassettoiD· 1 shared Anna SimoniD· 1 shared Anthony L. Forget· 1 shared Danielle Fuchs· 1 shared Diana J. LairdiD· 1 shared Eric Huang· 1 shared EunMi Jung· 1 shared Felicity Winkler· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperPharmacology & Toxicology

Andrea FrassettoORCID

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2 papers

Recent·Most cited

LNP Delivery of Prime Editors Enables Durable Correction of PAH R408W in Phenylketonuria Models

Stephanie Yazinski, Susanna Canali, Yang Xu, Xuling Zhu, James Nelson, Wenguo Gao, Zharko Daniloski, Wendy Leung-Owen, Felicity Winkler, Andrea Frassetto, Anna Simon, Jon N Penterman, Sean F. Maguire, Danielle Fuchs, James Rybarski, , Patrick F. Finn

This paper demonstrates the use of LNP-delivered prime editors to correct the PAH R408W mutation in PKU models, achieving ~50% correction efficiency.

bioRxiv · Oct 14, 2026 · PreprintPharmacology & Toxicology

Heterogeneity of transposon expression and activation of the repressive network in human fetal germ cells

Boris N Reznik, Steven A. Cincotta, Rebecca Garrett Jaszczak, Leslie J. Mateo, Joel Shen, Mei Cao, Laurence S. Baskin, Ping Ye, Wenfeng An, Diana J. Laird

The paper identifies heterogeneity in L1-ORF1p expression and its relationship with piRNA pathway activation and H3K9me3 levels in human fetal germ cells.

Development · Jan 18, 2019Peer-reviewedDevelopmental Biology

Boris N Reznik · henhao