Activation of a STAT3/LATS1 Signaling Axis by Folate Receptor α Enables Breast Cancer Cells to Resist Physiological Ferroptotic Stress
Prajakta Prasad Ambegaokar, Hira Lal Goel, Emmet R. Karner, Boris S. Dimitrov, Christi A. Silva, Arthur M. Mercurio
This study identifies a STAT3/LATS1 signaling axis mediated by folate receptor α that enables breast cancer cells to resist ferroptotic stress from ECM detachment and IKE treatment.
bioRxiv · Sep 18, 2026 · PreprintCancer Biology