Author

Ayush Kumar

University of Massachusetts Chan Medical SchoolORCID 0000-0002-2816-8345Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Assay:proteomics· 1

Frequent Co-Authors

Arthur M. MercurioiD· 2 shared Hira Lal Goel· 2 shared Boris S. Dimitrov· 1 shared Brendan A PachecoiD· 1 shared Christi A. Silva· 1 shared Christi A. Wisniewski· 1 shared Kensei KishimotoiD· 1 shared Lihua Julie ZhuiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCancer Biology

Arthur M. MercurioORCID

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2 papers

Recent·Most cited

Folate Receptor α Contributes to Radiation Resistance in Neuroendocrine Prostate Cancer by Regulating Redox Homeostasis

Hira Lal Goel, Tao Wang, Boris S. Dimitrov, Ayush Kumar, Christi A. Silva, Thomas J. FitzGerald, Arthur M. Mercurio

This study identifies folate receptor α as a key contributor to radiation resistance in neuroendocrine prostate cancer by maintaining redox homeostasis through the folate-FR axis.

bioRxiv · Mar 30, 2026 · PreprintCancer Biology

Resistance to Radiation Enhances Metastasis by Altering RNA Metabolism

Ayush Kumar, Kensei Kishimoto, Hira Lal Goel, Christi A. Wisniewski, Rui Li, Brendan A Pacheco, Lihua Julie Zhu, William A. Flavahan, Arthur M. Mercurio

This study shows that radiation resistance in TNBC enhances metastasis through RNA metabolism changes, specifically via HNRNPL-mediated circRNAs that regulate ITGβ3 expression.

Science Advances · Oct 17, 2025Peer-reviewedCancer Biology