A Yeast Global Genetic Screen Reveals that Metformin Induces an Iron Deficiency-Like State
Bram Stynen, Diala Abd-Rabbo, Jacqueline Kowarzyk, Leonor Miller‐Fleming, Markus Ralser, Stephen W. Michnick
The paper uses hdPCA to identify gene functions and pathways affected by metformin, revealing an iron deficiency-like cellular response.
bioRxiv · Sep 18, 2017 · PreprintSystems Biology