Diala Abd-Rabbo

This study shows that sequential infections in mice remodel immune landscapes, making them more similar to human immunity and affecting future immune responses.

This study identifies a spatially encoded interferon circuit that restricts progenitor exhausted CD8 T cells during chronic infection by enforcing niche sequestration and checkpoint control.

The paper identifies TOP2B binding sites as mutational hotspots in cancer genomes, showing their role in structural variants and driver mutations in genes like TP53 and MYC.

This study characterizes T cell glycosylation patterns across mouse and human tissues, revealing species-specific differences in glycan profiles and dynamics.

The paper characterizes mutation rate variability in regulatory elements across cancer genomes and identifies mutational signatures and drivers associated with specific genomic features.

ActivePathways integrates multivariate omics data to identify enriched pathways, revealing cancer driver genes and prognostic pathways in breast cancer.

The paper uses hdPCA to identify gene functions and pathways affected by metformin, revealing an iron deficiency-like cellular response.