Author
University of Pennsylvania
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
6 papers
Recent·Most cited
Max F. Dudek, Brandon M. Wenz, Benjamin F. Voight, Laura A. Almasy, Struan F.A. Grant
This study analyzes chromatin accessibility QTLs (caQTLs) to better understand how genetic variants influence trait heritability through regulatory mechanisms.
bioRxiv · Mar 20, 2026 · PreprintGenetics
Brandon M. Wenz, Max F. Dudek, Shweta Ramdas, Kate Townsend Creasy, Dong Xin, Kim M. Olthoff, Abraham A. Shaked, Daniel James Rader, Christopher D. Brown, Benjamin F. Voight
The paper integrates chromatin accessibility data with GWAS to identify regulatory mechanisms underlying blood lipid traits, finding 20% of signals lack proposed mechanisms.
The American Journal of Human Genetics · Feb 1, 2026Peer-reviewedGenetic & Genomic Medicine
Max F. Dudek, Brandon M. Wenz, Christopher D. Brown, Benjamin F. Voight, Laura A. Almasy, Struan F.A. Grant
The paper identifies 693 SNPs associated with transcription factor binding in liver ATAC-seq data by analyzing footprint quantitative trait loci (fpQTLs).
The American Journal of Human Genetics · Apr 17, 2025Peer-reviewedGenetics
Brandon M. Wenz, Yuan He, Nae-Chyun Chen, Joseph K. Pickrell, Jeremiah H. Li, Max F. Dudek, Taibo Li, Rebecca Keener, Benjamin F. Voight, Christopher D. Brown, Alexis J. Battle
The paper performs genotype inference from aggregated chromatin accessibility data to identify caQTLs and their links to gene expression and complex traits.
Genome biology · Mar 30, 2025Peer-reviewedGenomics
Katerina A.B. Gawronski, William P. Bone, YoSon Park, Evanthia E. Pashos, Brandon M. Wenz, Max F. Dudek, Xiao Wang, Wenli Yang, Daniel James Rader, Kiran Musunuru, Benjamin F. Voight, Christopher D. Brown
The paper identifies cell-type specific splicing quantitative trait loci (sQTLs) in iPSCs and HLCs and shows they contribute to lipid level variation beyond what is captured by gene expression alone.
Circulation Genomic and Precision Medicine · May 11, 2023Peer-reviewedGenetics
Shweta Ramdas, Jonathan Judd, Sarah E. Graham, Stavroula Kanoni, Yuxuan Wang, Ida L. Surakka, Brandon M. Wenz, Shoa L. Clarke, Alessandra Chesi, Andrew D. Wells, Konain Fatima Bhatti, Sailaja Vedantam, Thomas W. Winkler, Adam E. Locke, Eirini Marouli, , Maria Sabater‐Lleal
This paper integrates GWAS data with functional genomic datasets to identify regulatory mechanisms and causal genes underlying lipid-related traits.
The American Journal of Human Genetics · Aug 1, 2022Peer-reviewedGenomics