Alcohol use reduces the efficacy of anti-PD1 immunotherapy by disrupting anti-tumor immunity
Kristen N. Gilley, Jason A. Garness, Ali Younas Khan, Brandon W. Carpenter, Mitra Shabrang, Wolfgang Beckabir, Chad Victor Pecot, Benjamin Garrett Vincent, Leon G. Coleman
This study shows alcohol use reduces anti-PD1 immunotherapy efficacy in cancer patients and mouse models by impairing T cell function and anti-tumor immunity.
bioRxiv · Jul 14, 2025 · PreprintImmunology