Author

Breana Channer

Primary ORCID profile (0000-0003-2461-4894 · 2 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Breana ChanneriD2 papers · Drexel University

Biology Disciplines

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Bioengineering· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Andrew Tsourkas· 1 shared Aparajeeta Majumdar· 1 shared Carolann Espy· 1 shared Christopher A. HunteriD· 1 shared Dennis Discher· 1 shared Eno-Obong Essien· 1 shared Hamideh Parhiz· 1 shared I. E. Brodsky· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBioengineering

Andrew Tsourkas

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1 paper

Recent·Most cited

Lipid Nanoparticle-Associated Inflammation is Triggered by Sensing of Endosomal Damage: Engineering Endosomal Escape without Side Effects

Serena Omo-Lamai, Yufei Wang, Manthan N. Patel, Eno-Obong Essien, Mengwen Shen, Aparajeeta Majumdar, Carolann Espy, Jichuan Wu, Breana Channer, Michael Tobin, Shruthi Murali, Tyler E. Papp, Rhea Maheshwari, Liuqian Wang, Liam S. Chase, , Jacob S. Brenner

This paper identifies that lipid nanoparticle-induced inflammation arises from endosomal membrane damage and proposes strategies to mitigate it through galectin inhibition or ESCRT-recruiting lipids.

bioRxiv · Apr 16, 2024 · PreprintBioengineering