Author

Breana Channer

Drexel UniversityORCID 0000-0003-2461-4894Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Immunology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Peter J. GaskilliD· 3 shared Howard S. FoxiD· 2 shared Marzieh DanialiiD· 2 shared Stephanie M. MattiD· 2 shared Aleksa MilosavljeviciD· 1 shared Amirali AmirfallahiD· 1 shared Andrew TsourkasiD· 1 shared Anit ShahiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersImmunology

Peter J. GaskillORCID

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3 papers

Recent·Most cited

ImmunologybioRxivPreprintApr 25, 2026

It's Not Rewarding for Mitochondria: Dopamine-Induced Mitochondrial Dysfunction Activates cGAS-STING to Drive IL-6 Secretion in Macrophages

Marzieh Daniali, Breana Channer, Erin O. Curley…·Peter J. Gaskill

This paper identifies a pathway where dopamine induces mitochondrial dysfunction in macrophages, leading to IL-6 secretion via the cGAS-STING pathway.

DOI 10.64898/2026.04.23.719926

humanproteomics

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BioengineeringNature NanotechnologyPeer-reviewedAug 11, 2025

Lipid Nanoparticle-Associated Inflammation is Triggered by Sensing of Endosomal Damage: Engineering Endosomal Escape without Side Effects

Serena Omo‐Lamai, Yufei Wang, Manthan N. Patel…·Jacob Samuel Brenner

This paper identifies that lipid nanoparticle-induced inflammation arises from endosomal membrane damage and proposes strategies to mitigate it through galectin inhibition or ESCRT-recruiting lipids.

182 citationstop 1%

humanexperimental assay

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NeurosciencebioRxivPreprintJun 9, 2024

Dopamine-driven Increase in IL-1β in Myeloid Cells is Mediated by Differential Dopamine Receptor Expression and Exacerbated by HIV

Stephanie M. Matt, Rachel Nolan, Samyuktha Manikandan…·Peter J. Gaskill

This study shows dopamine increases IL-1β in myeloid cells via differential dopamine receptor expression, and this effect is exacerbated by HIV.

2 citations

humanbulk RNA-seq

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