Tumor-Initiating Cells Fine-tune the Plasticity of Neutrophils to Sculpt a Protective Niche
Weijie Guo, Jingyun Luan, Xuejie Huang, Daniel Leon, Sophie Gang, Benjamin Nicholson, Breanna Bertacchi, Diana Bolotin, Mark William Lingen, Alexander T. Pearson, Evgeny Izumchenko, Ari Joseph Rosenberg, Nishant Agrawal, Everett E. Vokes, Siwakorn Punyawatthananukool, , Yuxuan Miao
This study identifies tumor-initiating cells that modulate neutrophil plasticity to create a protective niche, preventing immunotherapy effectiveness.
Cancer Cell · Dec 4, 2025Peer-reviewedCancer Biology