Morphine Suppresses Peripheral Responses and Transforms Brain Myeloid Gene Expression to Favor Neuropathogenesis in SIV Infection
Howard S. Fox, Meng Niu, Brenda Morsey, Benjamin G. Lamberty, Katy M. Emanuel, Palsamy Periyasamy, Shannon E. Callen, Arpan Acharya, Gregory Kubik, James D. Eudy, Chittibabu Guda, Shetty Ravi Dyavar, Courtney Vail Fletcher, Siddappa N. Byrareddy, Shilpa J. Buch
This study shows morphine suppresses immune responses and alters brain myeloid gene expression in SIV-infected macaques, promoting neuropathogenesis.
Frontiers in Immunology · Nov 16, 2022Peer-reviewedNeuroscience