Arpan Acharya

The paper identifies IL-17A, STAT1, CEBPB, and cGAS-STING as key drivers of HIV-associated neuroinflammation using HIV-infected cerebral organoids and validates findings in a primate model.

The paper investigates tissue-specific metabolic reprogramming and gut dysbiosis in hamsters infected with SARS-CoV-2 variants, revealing differences in viremia, metabolic responses, and microbiota composition between delta and omicron variants.

This study shows morphine suppresses immune responses and alters brain myeloid gene expression in SIV-infected macaques, promoting neuropathogenesis.

The paper identifies and evaluates two potent SARS-CoV-2 entry inhibitors through computational screening and in vitro testing, showing synergy with remdesivir.

This study shows that chronic morphine administration reduces SIV reservoirs in peripheral blood and lymph nodes but increases them in CNS microglia/macrophages in SIV-infected rhesus macaques.