Author

Shilpa J. Buch

University of Nebraska Medical CenterORCID 0000-0002-3103-6685Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:non-human primate· 1 Organism:rat· 1 Approach:statistical model· 1

Frequent Co-Authors

Arpan AcharyaiD· 2 shared Benjamin G. Lamberty· 2 shared Brenda Morsey· 2 shared Howard S. FoxiD· 2 shared Shannon E. CalleniD· 2 shared Siddappa N. ByrareddyiD· 2 shared Chittibabu GudaiD· 1 shared Courtney Vail FletcheriD· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersNeuroscience

Arpan AcharyaORCID

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2 papers

Recent·Most cited

Morphine Suppresses Peripheral Responses and Transforms Brain Myeloid Gene Expression to Favor Neuropathogenesis in SIV Infection

Howard S. Fox, Meng Niu, Brenda Morsey, Benjamin G. Lamberty, Katy M. Emanuel, Palsamy Periyasamy, Shannon E. Callen, Arpan Acharya, Gregory Kubik, James D. Eudy, Chittibabu Guda, Shetty Ravi Dyavar, Courtney Vail Fletcher, Siddappa N. Byrareddy, Shilpa J. Buch

This study shows morphine suppresses immune responses and alters brain myeloid gene expression in SIV-infected macaques, promoting neuropathogenesis.

Frontiers in Immunology · Nov 16, 2022Peer-reviewedNeuroscience

Chronic morphine administration differentially modulates viral reservoirs in SIVmac251 infected rhesus macaque model

Arpan Acharya, Omalla Allan Olwenyi, Michellie Thurman, Kabita Pandey, Brenda Morsey, Benjamin G. Lamberty, Natasha Ferguson, Shannon E. Callen, Fang Qiu, Shilpa J. Buch, Howard S. Fox, Siddappa N. Byrareddy

This study shows that chronic morphine administration reduces SIV reservoirs in peripheral blood and lymph nodes but increases them in CNS microglia/macrophages in SIV-infected rhesus macaques.

Journal of Virology · Dec 16, 2020Peer-reviewedMolecular Biology