Paclitaxel-induced mitotic arrest results in a convergence of apoptotic dependencies that can be safely exploited by BCL-XL degradation to overcome cancer chemoresistance
Xingping Qin, Adam G. Presser, Lissah Johnson, Yusuke Matoba, Brendan Shay, Weiyi Xu, Jonathan Choiniere, Cameron Fraser, Filip Garbicz, Johan K. E. Spetz, Stacey J. Yu, Mary H.C. Florido, Francesca Picucci, Yang Yang, Ronny Drapkin, , Kristopher A. Sarosiek
bioRxiv · Jun 24, 2025 · PreprintCancer Biology