The regulatory landscape of optic fissure closure in the vertebrate eye
Brian Ho Ching Chan, Mariya Moosajee, Holly Hardy, James G. D. Prendergast, Joe Rainger
The paper identifies cis-regulatory elements and transcription factors involved in optic fissure closure using chicken embryos, linking them to human coloboma genes.
bioRxiv · Feb 14, 2026 · PreprintDevelopmental Biology