The paper generates a Netrin-1 fluorescent reporter chicken line to study molecular signatures during optic fissure closure and identifies new markers and pathways for developmental tissue fusion.

DOI 10.1101/2024.10.01.616014

experimental assaycell type annotation

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Developmental BiologybioRxivPreprintFeb 22, 2022

Estrogen suppresses DMRT1 expression during ovarian development in the chicken

Debiao Zhao, Long Liu, Sunil Nandi…·Michael Clinton

The paper shows estrogen reduces DMRT1 protein levels in female chicken gonads during ovarian development, suggesting estrogen signaling regulates primary sex determination.

3 citations

experimental assay

𝕏 PostBluesky

Developmental BiologyProceedings of the National Academy of SciencesPeer-reviewedMar 3, 2021

Primary sex determination in chickens depends on DMRT1 dosage, but gonadal sex does not determine secondary sexual characteristics in adult birds

Jason Ioannidis, Güneş Taylor, Debiao Zhao…·Michael Clinton

180 citationstop 1%

experimental assay

𝕏 PostBluesky