Author

Nicholas Owen

University College LondonORCID 0000-0001-5598-6274Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Genetics· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

Mariya MoosajeeiD· 3 shared Berthold SeitziD· 1 shared Brian Ho Ching Chan· 1 shared Camille LaberthonnìèreiD· 1 shared Cécile MéjécaseiD· 1 shared Daniel AberdamiD· 1 shared Dulce Lima CunhaiD· 1 shared Hajrah Sarkar· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersPathology

Mariya MoosajeeORCID

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3 papers

Recent·Most cited

PathologyFrontiers in Cell and Developmental BiologyPeer-reviewedApr 29, 2025

Dominant RDH12-retinitis pigmentosa impairs photoreceptor development and cone function in retinal organoids

Cécile Méjécase, Ya Zhou, Nicholas Owen…·Mariya Moosajee

This study generates a retinal organoid model of dominant RDH12-retinitis pigmentosa, showing impaired photoreceptor development and cone function.

6 citations

humanorganoid / primary culture

𝕏 PostBluesky

GeneticsBiomoleculesPeer-reviewedFeb 4, 2023

Identification of novel coloboma candidate genes through conserved gene expression analyses across four vertebrate species

Violeta Trejo-Reveles, Nicholas Owen, Brian Ho Ching Chan…·Joe Rainger

The paper identifies 10 genes with conserved expression in the optic fissure across vertebrates and suggests EMX2, NID1, and EPHB3 as novel candidate genes for ocular coloboma.

10 citations

𝕏 PostBluesky

Developmental BiologybioRxivPreprintJul 13, 2022

Multi-omics analyses identify transcription factor interplay in corneal epithelial fate determination and disease

Jos G.A. Smits, Dulce Lima Cunha, Maryam Amini…·Huiqing Zhou

The paper identifies transcription factor interplay in corneal epithelial fate determination and disease using multi-omics analyses of limbal stem cells and epidermal keratinocytes.

2 citations

𝕏 PostBluesky