Author

Brianna E. Hegarty

Georgia Institute of Technology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3 Animal Behavior & Cognition· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Approach:statistical model· 4 Research Focus:differential expression· 3 Research Focus:gene regulatory network inference· 3 Organism:zebrafish· 3 Research Focus:cell-cell communication· 2 Approach:experimental assay· 2 Assay:scRNA-seq· 2

Frequent Co-Authors

George W. GruenhageniD· 4 shared Jeffrey Todd StreelmaniD· 4 shared Zachary V. JohnsoniD· 4 shared Abigail R. Histed· 1 shared Arjen J. BoenderiD· 1 shared Coltan G. ParkeriD· 1 shared Cristina M. BakeriD· 1 shared Ewoud R.E. SchmidtiD· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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4 shared papersNeuroscience

George W. GruenhagenORCID

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4 papers

Recent·Most cited

Adult sex change leads to extensive forebrain reorganization in clownfish

Coltan G. Parker, George W. Gruenhagen, Brianna E. Hegarty, Abigail R. Histed, Jeffrey Todd Streelman, Justin S. Rhodes, Zachary V. Johnson

This study uses single nucleus RNA-sequencing to analyze sex differences in the forebrain of clownfish, identifying molecular and cellular changes associated with adult sex change.

Biology of Sex Differences · Jul 23, 2024Peer-reviewedNeuroscience

Spatially resolved cell atlas of the teleost telencephalon and deep homology of the vertebrate forebrain

Brianna E. Hegarty, George W. Gruenhagen, Zachary V. Johnson, Cristina M. Baker, Jeffrey Todd Streelman

The paper generates a spatially-resolved transcriptional atlas of the cichlid fish telencephalon and compares it to tetrapod forebrain regions, revealing conserved cell-type similarities.

Communications Biology · May 21, 2024Peer-reviewedNeuroscience

Natural variation in oxytocin receptor signaling causes widespread changes in brain transcription: a link to the natural killer gene complex

Arjen J. Boender, Zachary V. Johnson, Kayla K. Green, George W. Gruenhagen, Brianna E. Hegarty, Kengo Horie, Kiyoshi Inoue, Ewoud R.E. Schmidt, Jeffrey Todd Streelman, Hasse Walum, Larry J. Young

This study links natural variation in oxytocin receptor signaling to changes in brain transcription, particularly in the natural killer gene complex, suggesting a mechanism for social behavior diversity.

bioRxiv · Oct 26, 2023 · PreprintNeuroscience

Cellular profiling of a recently-evolved social behavior

Zachary V. Johnson, Brianna E. Hegarty, George W. Gruenhagen, Tucker J. Lancaster, Patrick T. McGrath, Jeffrey Todd Streelman

The paper uses snRNA-seq and comparative genomics to study the evolution of bower building behavior in Lake Malawi cichlids, identifying glial gene module changes linked to the behavior.

bioRxiv · Aug 9, 2022 · PreprintAnimal Behavior & Cognition