The myokine FGF21 associates with enhanced survival in ALS and mitigates stress-induced cytotoxicity
Abhishek Guha, Ying Si, Reed Smith, Mohamed Kazamel, Nan Jiang, Katherine A. Smith, Anna Elizabeth Thalacker‐Mercer, Brijesh K. Singh, Ritchie Ho, Shaida A. Andrabi, Joao D. Tavares Da Silva Pereira, Juliana S. Salgado, Manasi Agrawal, Emina Horvat Velić, Peter H. King
This study identifies FGF21 as a biomarker in ALS associated with slower disease progression and protective effects against stress-induced cytotoxicity.
bioRxiv · Sep 11, 2024 · PreprintNeuroscience