Inhibition of the RNA Regulator HuR mitigates spinal cord injury by potently suppressing post-injury neuroinflammation
Mohammed Amir Husain, Reed Smith, Robert E. Sorge, Abdulraheem Kaimari, Ying Si, Ali Z. Hassan, Abhishek Guha, Katherine A. Smith, Christopher P. Cardozo, Jennifer J. DeBerry, Shaida A. Andrabi, Burt Nabors, Natalia Filippova, Caroline K. Webb, Peter H. King
This study shows that inhibiting HuR with SRI-42127 reduces neuroinflammation and improves functional outcomes after spinal cord injury.
The FASEB Journal · May 2, 2025Peer-reviewedNeuroscience