NINJ1 is activated by calcium-driven plasma membrane lipid scrambling during lytic cell death
Jazlyn P. Borges, Yongqian Wang, Liron David, Allen Volchuk, Brunna Martins, Ruiqi Cai, Hao Wu, Spencer A. Freeman, Neil M. Goldenberg, Michael W. Salter, Benjamin Ethan Steinberg
The paper identifies calcium-driven lipid scrambling as the mechanism activating NINJ1-mediated plasma membrane rupture during lytic cell death.
bioRxiv · Oct 23, 2024 · PreprintCell Biology