Aberrations in stromal signaling, muscle contractility and epithelial architecture underlie poor embryo-implantation outcomes after murine ovarian stimulation
Harini Raghu Kumar, Manoj Madhavan, Lisa Zou, C N Chen, Ryan Yoder, Gregory W. Burns, Emmanuel N. Paul, Nataki C. Douglas, Ripla Arora
This study shows that ovarian stimulation disrupts uterine structure and function in mice, leading to poor embryo implantation, and identifies PDGFRA signaling as a key factor.
bioRxiv · Jun 17, 2026 · PreprintDevelopmental Biology