Jinghui Guo

β-cell-specific Non-invasive Ultrasound Stimulation to Enhance Insulin Release and Glucose Control in Mice

This study uses ultrasound with microbubbles to stimulate beta-cells in mice, enhancing insulin release and reducing blood glucose levels without tissue damage.

Mechano-regulation of GLP-1 production by Piezo1 in intestinal L cells

This study shows that Piezo1 in intestinal L cells mechanically regulates GLP-1 production, affecting glucose tolerance and diabetes.

The mechanosensitive ion channel Piezo1 contributes to ultrasound neuromodulation

This study shows that Piezo1 mediates ultrasound neuromodulation in the brain by demonstrating reduced neuronal responses in Piezo1 knockout mice.

The mechanosensitive ion channel Piezo1 modulates the migration and immune response of microglia

This study shows that Piezo1 modulates microglia migration and immune responses by affecting cytokine production and stiffness sensing.

Circuit-specific sonogenetic stimulation of the deep brain elicits distinct signaling and behaviors in freely moving mice

This study demonstrates that sonogenetics can selectively activate defined neural circuits and induce specific behaviors in freely moving mice through ultrasound stimulation.

Ultrasound neuromodulation through nanobubble-actuated sonogenetics

This paper demonstrates a method using gas-filled nanostructures to enhance and selectively control ultrasound neuromodulation of neurons.