Nataki C. Douglas

This paper develops a 3D in vitro model of ovarian follicle-endometrial organoid co-culture that mimics ovarian control of endometrial decidualization, showing similar but distinct transcriptional patterns compared to traditional hormone-based methods.

The paper examines endometrial folding and secretory activity during the menstrual cycle to identify markers of endometrial receptivity.

This study shows that ovarian stimulation disrupts uterine structure and function in mice, leading to poor embryo implantation, and identifies PDGFRA signaling as a key factor.

This study compares cAMP and EPC-induced decidualization in 3D human endometrial organoids, finding that EPC induces broader and more physiologically relevant transcriptional changes.

The paper maps the human endometrium and first trimester decidua using single-cell RNA sequencing to identify gene expression changes linked to fertility and implantation.

This study investigates the effects of long- and short-chain PFAS on ovarian function in mice, finding that long-chain PFAS disrupt follicle maturation and ovulation via PPARγ activation.

This study investigates the dose-response effects of FSH on mouse folliculogenesis using single-cell RNA sequencing, revealing gene expression patterns and potential molecular mechanisms of FSH-induced ovarian disorders.