PDZD-8 interacts with LGG-2/LC3 to promote autolysosome formation
Alexandre Pouget, Valentin Meire, Céline Largeau, Claire Boulogne, Baptiste Roelens, Diego Javier Zea, Christophe Lefebvre, Renaud Legouis, Emmanuel Culetto
This study identifies PDZD-8 as an ER protein that interacts with LGG-2/LC3 to promote autolysosome formation by bridging ER-autophagosome contacts.
bioRxiv · Jan 28, 2026 · PreprintCell Biology