Baptiste Roelens

This study identifies PDZD-8 as an ER protein that interacts with LGG-2/LC3 to promote autolysosome formation by bridging ER-autophagosome contacts.

The paper identifies DSB-3 as a meiotic DSB-promoting protein in C. elegans, showing both conservation with and divergence from homologous complexes in other organisms.

This study identifies the HAL-2/HAL-3 complex as essential for regulating Polo-like kinase activity during C. elegans meiosis, ensuring proper homolog pairing and synaptonemal complex assembly.

This study identifies NBS-1 as essential for processing meiotic DSBs to promote crossover formation and antagonize error-prone repair, ensuring genome integrity.

This study shows that meiotic recombination modulates the stability of the synaptonemal complex in C. elegans, with PLK-2 playing a key role in this process.