Enhanced Protection from SARS-CoV-2 Variants by MVA-Based Vaccines Expressing Matched or Mismatched S Proteins Administered Intranasally to hACE2 Mice
C. A. Cotter, J. L. Americo, P. L. Earl, B. Moss
This study evaluates MVA-based vaccines with matched or mismatched S proteins against SARS-CoV-2 variants in hACE2 mice, showing that mismatched vaccines still provide protection, especially when administered intranasally.
bioRxiv · Dec 3, 2022 · PreprintMicrobiology