Author

R. Solari

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

E. W. Tate· 3 shared M. Faronato· 2 shared W. W. Kallemeijn· 2 shared A. Gorelik· 1 shared A. Goya Grocin· 1 shared A. J. van Waardenberg· 1 shared A. S. Bell· 1 shared B. Brzezicha· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersMicrobiology

E. W. Tate

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Inhibition of host N-myristoylation compromises the infectivity of SARS-CoV-2 due to Golgi-bypassing egress from lysosomes and endoplasmic reticulum

S. H. Saber, M. R. Shaker, J. Sng, N. Yak, S. D. Morrison, S. Pars, H. Zheng, G. Pietrogrande, T. Binder, S. Lu, M. Floetenmeyer, R. Ojha, T. Quirin, J. Ruuska, T. Smura, , M. Joensuu

This study shows that inhibiting host N-myristoylation reduces SARS-CoV-2 infectivity by impairing viral envelope protein maturation and causing Golgi-bypassing egress.

bioRxiv · Mar 3, 2023 · PreprintMicrobiology

Inhibition of vaccinia virus L1 N-myristoylation by the host N-myristoyltransferase inhibitor IMP-1088 generates non-infectious virions defective in cell entry

L. Priyamvada, W. W. Kallemeijn, M. Faronato, K. Wilkins, C. S. Goldsmith, C. A. Cotter, S. Ojeda, R. Solari, B. Moss, E. W. Tate, P. S. Satheshkumar

This study shows that IMP-1088 inhibits vaccinia virus infection by blocking N-myristoylation of viral protein L1, leading to non-infectious virions.

bioRxiv · Jun 13, 2022Microbiology

N-myristoyltransferase inhibition is synthetic lethal in MYC-deregulated cancers

G. A. Lueg, M. Faronato, A. Gorelik, A. Goya Grocin, E. Caamano-Gutierrez, F. Falciani, R. Solari, R. Carr, A. S. Bell, E. Bartlett, J. A. Hutton, M. Llorian-Sopena, P. Chakravarty, B. Brzezicha, M. Janz, , E. W. Tate

N-myristoyltransferase inhibition causes mitochondrial dysfunction and cell death in MYC-deregulated cancers through post-transcriptional failure in complex I synthesis.

bioRxiv · Mar 20, 2021 · PreprintCancer Biology