Author

C. B. Whitchurch

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 6 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:bacteria (other)· 4 Research Focus:cell signaling & trafficking· 4 Research Focus:cell type annotation· 4 Research Focus:host-pathogen & immune response· 2 Assay:imaging· 2 Approach:microscopy & imaging analysis· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

L. M. Nolan· 4 shared L. Turnbull· 3 shared J. J. Lazenby· 2 shared L. C. McCaughey· 2 shared A. L. Bottomley· 1 shared A. L. Hynen· 1 shared B. S. Ahluwalia· 1 shared C. Holte· 1 shared

Activity by Year

2019-2024 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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4 shared papersMicrobiology

L. M. Nolan

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Author profile →

7 papers

Recent·Most cited

FakA impacts antiseptic susceptibility in Staphylococcus aureus and Enterococcus faecalis

M. Solsona Gaya, H. Felgate, H. Siani, C. B. Whitchurch, M. A. Webber

This study shows Staphylococcus aureus and Enterococcus faecalis can evolve tolerance to biocides like chlorhexidine and octenidine, with FakA playing a key role in this adaptation.

bioRxiv · Feb 13, 2024 · PreprintMicrobiology

Effect of caffeine and other xanthines on liver sinusoidal endothelial cell ultrastructure

H. Mao, K. Szafranska, L. Kruse, C. Holte, D. L. Wolfson, B. S. Ahluwalia, C. B. Whitchurch, L. Cole, G. P. Lockwood, R. Diekmann, D. G. Le Couteur, V. C. Cogger, P. A. G. McCourt

The paper examines the effects of caffeine and other xanthines on liver sinusoidal endothelial cell ultrastructure, finding no toxic effects but changes in fenestration frequency and porosity at high concentrations.

bioRxiv · Jan 20, 2023Cell Biology

Bacteriophage infection produces membrane vesicles in Escherichia coli via both explosive cell lysis and membrane blebbing

P. K. Mandal, G. B. Ballerin, L. M. Nolan, N. K. Petty, C. B. Whitchurch

bioRxiv · Dec 23, 2020Microbiology

Multiple Holins Contribute to Extracellular DNA Release in Pseudomonas aeruginosa Biofilms

A. L. Hynen, J. J. Lazenby, G. M. Savva, L. C. McCaughey, L. Turnbull, L. M. Nolan, C. B. Whitchurch

This study identifies three holins involved in eDNA release during Pseudomonas aeruginosa biofilm development, showing their role in microcolony formation and eDNA release dynamics.

bioRxiv · Oct 28, 2020Microbiology

Pseudomonas aeruginosa is capable of natural transformation in biofilms

L. M. Nolan, L. Turnbull, M. Katrib, S. R. Osvath, D. Losa, J. J. Lazenby, C. B. Whitchurch

This study shows Pseudomonas aeruginosa in biofilms can undergo natural transformation, challenging previous assumptions about its capability.

bioRxiv · Apr 6, 2020Microbiology

Characterising the mechanism of action of an ancient antimicrobial, honey, using modern transcriptomics

D. Bouzo, N. N. Cokcetin, L. Li, G. Ballerin, A. L. Bottomley, J. Lazenby, C. B. Whitchurch, I. T. Paulsen, K. A. Hassan, E. J. Harry

This study uses transcriptomics to show that manuka honey's antimicrobial action involves multiple mechanisms, including SOS response, oxidative damage, and membrane disruption, without promoting bacterial resistance.

bioRxiv · Feb 12, 2020 · PreprintMicrobiology

ChpC controls twitching motility-mediated expansion of Pseudomonas aeruginosa biofilms in response to serum albumin, mucin and oligopeptides

L. M. Nolan, L. C. McCaughey, J. Merjane, L. Turnbull, C. B. Whitchurch

This study shows ChpC is required for Pseudomonas aeruginosa twitching motility response to serum albumin, mucin, and oligopeptides, while cAMP and T4P levels are independent of ChpC.

bioRxiv · Oct 31, 2019Microbiology