Author

I. T. Paulsen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 10

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:cell type annotation· 5 Organism:bacteria (other)· 4 Assay:bulk RNA-seq· 4 Research Focus:host-pathogen & immune response· 4 Assay:metagenomics· 4 Research Focus:gene regulatory network inference· 3 Approach:statistical model· 3

Frequent Co-Authors

K. A. Hassan· 6 shared A. Focardi· 2 shared L. Li· 2 shared S. G. Tetu· 2 shared T. M. Ghaly· 2 shared V. N. Naidu· 2 shared A. Berim· 1 shared A. K. Cain· 1 shared

Activity by Year

2020-2023 · peak 5/yr

Co-Author Collaboration Network

10 top collaborators · 9 mutual co-author links

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6 shared papersMicrobiology

K. A. Hassan

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10 papers

Recent·Most cited

The Acinetobacter baumannii virulence factor Omp33 is important for tolerance to benzalkonium chloride

V. N. Naidu, B. S. Shah, K. A. Hassan, I. T. Paulsen

This study identifies Omp33 as a key factor in Acinetobacter baumannii's tolerance to benzalkonium chloride by showing its role in preventing BAC entry and enhancing stress resistance.

bioRxiv · Jul 26, 2023 · PreprintMicrobiology

Krumholzibacteriota and Deltaproteobacteria contain rare genetic potential to liberate carbon from monoaromatic compounds in subsurface coal seams

B. C. Campbell, P. Greenfield, S. Gong, D. Midgley, I. T. Paulsen, S. C. George

This study identifies three microbial taxa with genetic potential to degrade monoaromatic compounds in subsurface coal seams, including a novel Krumholzibacteriota species.

bioRxiv · Jul 10, 2023Microbiology

Stratified microbial communities in Australia's only anchialine cave are taxonomically novel and drive chemotrophic energy production via coupled nitrogen-sulphur cycling

T. M. Ghaly, A. Focardi, L. D. H. Elbourne, B. Sutcliffe, B. F. Humphreys, I. T. Paulsen, S. G. Tetu

This study uses shotgun metagenomics to analyze microbial communities in Bundera Sinkhole, revealing novel taxa and chemotrophic energy production through nitrogen-sulphur cycling.

bioRxiv · Apr 3, 2023Microbiology

Plastic Leachate Exposure Drives Antibiotic Resistance and Virulence in Marine Bacterial Communities

E. J. Vlaanderen, T. M. Ghaly, L. R. Moore, A. Focardi, I. T. Paulsen, S. G. Tetu

This study shows that plastic leachate increases antibiotic resistance and virulence genes in marine bacterial communities without the presence of plastic surfaces.

bioRxiv · Feb 13, 2023Microbiology

AadT, a new weapon in Acinetobacters fight against antibiotics

V. N. Naidu, B. Shah, C. Maher, I. T. Paulsen, K. A. Hassan

The paper identifies AadT, a new multidrug efflux pump in Acinetobacter, which reduces susceptibility to multiple antimicrobials and is associated with resistance genes.

bioRxiv · Jan 3, 2023 · PreprintMicrobiology

Intermittent fasting has a diet-specific impact on the gut microbiota and colonic mucin O-glycosylation of mice

H. K. A. H. Gamage, A. M. M. Sathili, K. Nishtala, R. W. W. Chong, N. H. Packer, I. T. Paulsen

This study examines how intermittent fasting affects gut microbiota and mucin O-glycosylation in mice on different diets, finding diet-specific changes in microbial communities and glycan structures.

bioRxiv · Sep 15, 2022 · PreprintMicrobiology

The effect of root exudates on the transcriptome of rhizosphere Pseudomonas spp.

O. V. Mavrodi, J. R. McWilliams, J. O. Peter, A. Berim, K. A. Hassan, L. D. Elbourne, M. K. LeTourneau, D. R. Gang, I. T. Paulsen, D. M. Weller, L. S. Thomashow, A. S. Flynt, D. Mavrodi

This study investigates how root exudates from Brachypodium distachyon affect the transcriptome of Pseudomonas fluorescens strains, revealing gene expression changes related to metabolism and adaptation.

bioRxiv · Jan 8, 2021 · PreprintMicrobiology

The molecular basis of Acinetobacter baumannii cadmium toxicity and resistance

S. F. Alquethamy, F. G. Adams, R. Maharjan, N. N. Delgado, M. Zang, J. C. Paton, K. A. Hassan, I. T. Paulsen, C. A. McDevitt, A. K. Cain, B. A. Eijkelkamp

This study identifies CzcE and the CzcCBA efflux system as key factors in A. baumannii's resistance to cadmium stress and reveals metal ion homeostasis changes under cadmium exposure.

bioRxiv · Oct 20, 2020Microbiology

Spermidine and spermine are the natural substrates of the Acinetobacter baumannii AmvA multidrug efflux pump

F. L. Short, Q. Liu, H. E. Ashwood, V. Naidu, L. Li, B. C. Mabbutt, K. A. Hassan, I. T. Paulsen

This study identifies spermidine and spermine as natural substrates of the Acinetobacter baumannii AmvA efflux pump, revealing its role in polyamine transport and antibiotic resistance.

bioRxiv · Oct 2, 2020 · PreprintMicrobiology

Characterising the mechanism of action of an ancient antimicrobial, honey, using modern transcriptomics

D. Bouzo, N. N. Cokcetin, L. Li, G. Ballerin, A. L. Bottomley, J. Lazenby, C. B. Whitchurch, I. T. Paulsen, K. A. Hassan, E. J. Harry

This study uses transcriptomics to show that manuka honey's antimicrobial action involves multiple mechanisms, including SOS response, oxidative damage, and membrane disruption, without promoting bacterial resistance.

bioRxiv · Feb 12, 2020 · PreprintMicrobiology