Noroviruses subvert the core stress granule component G3BP1 to promote viral VPg-dependent translation.
M. Hosmillo, J. Lu, M. R. McAllaster, J. B. Eaglesham, X. Wang, E. Emmott, P. Domingues, Y. Chaudhry, T. J. Fitzmaurice, M. K. H. Tung, M. Panas, G. McInerney, N. Locker, C. B. Willen, I. Goodfellow
This study identifies G3BP1 as a host factor essential for norovirus infection and reveals its role in VPg-dependent translation initiation.
bioRxiv · Mar 8, 2019Microbiology