Discerning Specific Thrombolytic Activities and Blood Clot Degradomes of Diverse Snake Venoms with Untargeted Peptidomics
Cara Francesca Smith, Mamadou Aliou Baldé, Stephanie French, Cassandra M. Modahl, Lilyrose Bahrabadi, Merilyn Amponsah-Asamoah, Keira Y. Larson, Sean P. Maroney, David Ceja Galindo, Martin Millimouno, Naby Camara, Jordan Max Benjamin, Nicklaus Brandehoff, Maxwell C. McCabe, Mitchell J. Cohen, , Anthony J. Saviola
This study uses untargeted peptidomics and thrombolysis assays to analyze the clot-degrading effects of six snake venoms, revealing specific targets and mechanisms of thrombolysis.
Journal of Thrombosis and Haemostasis · Mar 22, 2025Peer-reviewedPharmacology & Toxicology