Author

Cara Francesca Smith

Liverpool School of Tropical MedicineORCID 0000-0002-6868-7713Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Evolutionary Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:proteomics· 1 Approach:statistical model· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Anthony J. SaviolaiD· 1 shared C. Balde· 1 shared Cassandra M. ModahliD· 1 shared David Ceja GalindoiD· 1 shared Elda Eliza SancheziD· 1 shared Jordan Max BenjaminiD· 1 shared Jory van ThieliD· 1 shared Kate JacksoniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperPharmacology & Toxicology

Anthony J. SaviolaORCID

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2 papers

Recent·Most cited

The genomic origins and evolutionary path to a key innovation in the world's most venomous snakes

Jory van Thiel, Noah L. Dowell, Cara Francesca Smith, Elda Eliza Sanchez, Sean B. Carroll

This study traces the genomic origins of four procoagulant venom toxins in Australian snakes and identifies a fifth toxin, showing two distinct evolutionary paths for their development.

Proceedings of the National Academy of Sciences · Sep 4, 2026Peer-reviewedEvolutionary Biology

Discerning Specific Thrombolytic Activities and Blood Clot Degradomes of Diverse Snake Venoms with Untargeted Peptidomics

Cara Francesca Smith, Mamadou Aliou Baldé, Stephanie French, Cassandra M. Modahl, Lilyrose Bahrabadi, Merilyn Amponsah-Asamoah, Keira Y. Larson, Sean P. Maroney, David Ceja Galindo, Martin Millimouno, Naby Camara, Jordan Max Benjamin, Nicklaus Brandehoff, Maxwell C. McCabe, Mitchell J. Cohen, , Anthony J. Saviola

This study uses untargeted peptidomics and thrombolysis assays to analyze the clot-degrading effects of six snake venoms, revealing specific targets and mechanisms of thrombolysis.

Journal of Thrombosis and Haemostasis · Mar 22, 2025Peer-reviewedPharmacology & Toxicology