The Structural Role of N170 in Substrate-assisted Deacylation in KPC-2 β-Lactamase
D. Parwana, J. Gu, S. Chen, C. Bethel, E. K. Marshall, A. M. Hujer, R. A. Bonomo, S. Haider
This study investigates the structural role of N170 in substrate-assisted deacylation in KPC-2 β-lactamase, revealing its impact on drug binding and catalytic activity.
bioRxiv · May 22, 2023Biophysics