Author

C. Bosdotter

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Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

A. Lerma Clavero· 1 shared B. Vojtesek· 1 shared D. P. Lane· 1 shared F. Wermeling· 1 shared K. Ingelshed· 1 shared L. Jiang· 1 shared P. Kannan· 1 shared P. Lafqvist Boqvist· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperCancer Biology

A. Lerma Clavero

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1 paper

Recent·Most cited

MDM2 inhibitors, nutlin-3a and navtemadelin, retain efficacy in human and mouse cancer cells cultured in hypoxia

A. Lerma Clavero, P. Lafqvist Boqvist, K. Ingelshed, C. Bosdotter, S. Sedimbi, L. Jiang, F. Wermeling, B. Vojtesek, D. P. Lane, P. Kannan

This study shows that MDM2 inhibitors nutlin-3a and navtemadelin remain effective in hypoxic conditions in human and mouse cancer cells with wild-type p53, but not in mutant or null p53 cells.

bioRxiv · Oct 20, 2022Cancer Biology